Gastrointestinale Hormone

Gastrointestinale Hormone (Synonym: Enterohormone) werden von Zellen des Magen-Darm-Traktes sezerniert. Sie beeinflussen direkt und indirekt die Verdauung, metabolische Prozesse und sind gemeinsam mit nervaler Informationsübertragung an der Regulation von Hunger und Sättigung beteiligt. Ihre Wirkung kann sich endokrin, parakrin und autokrin entfalten. Wichtige gastrointestinale Hormone sind zum Beispiel Ghrelin, Gastrin, Sekretin, Cholecystokinin, GLP-1 und viele weitere. Auch Metabolite des Mikrobioms wirken als Hormone.

Einzelnachweise

↑ Atsukazu Kuwahara, Kyoko Matsuda, Yuko Kuwahara, Shinji Asano, Toshio Inui: Microbiota-gut-brain axis: enteroendocrine cells and the enteric nervous system form an interface between the microbiota and the central nervous system. In: Biomedical Research (Tokyo, Japan). Band 41, Nr. 5, 2020, ISSN 1880-313X, S. 199–216, doi:10.2220/biomedres.41.199, PMID 33071256.
↑ Elena Valassi, Massimo Scacchi, Francesco Cavagnini: Neuroendocrine control of food intake. In: Nutrition, metabolism, and cardiovascular diseases: NMCD. Band 18, Nr. 2, Februar 2008, ISSN 1590-3729, S. 158–168, doi:10.1016/j.numecd.2007.06.004, PMID 18061414.
↑ Alyce M. Martin, Emily W. Sun, Damien J. Keating: Mechanisms controlling hormone secretion in human gut and its relevance to metabolism. In: The Journal of Endocrinology. Band 244, Nr. 1, 29. November 2019, ISSN 1479-6805, S. R1–R15, doi:10.1530/JOE-19-0399, PMID 31751295, PMC 6892457 (freier Volltext).
↑ Atsukazu Kuwahara, Kyoko Matsuda, Yuko Kuwahara, Shinji Asano, Toshio Inui: Microbiota-gut-brain axis: enteroendocrine cells and the enteric nervous system form an interface between the microbiota and the central nervous system. In: Biomedical Research (Tokyo, Japan). Band 41, Nr. 5, 2020, ISSN 1880-313X, S. 199–216, doi:10.2220/biomedres.41.199, PMID 33071256.
↑ Gerard Clarke, Roman M. Stilling, Paul J. Kennedy, Catherine Stanton, John F. Cryan: Minireview: Gut microbiota: the neglected endocrine organ. In: Molecular Endocrinology (Baltimore, Md.). Band 28, Nr. 8, August 2014, ISSN 1944-9917, S. 1221–1238, doi:10.1210/me.2014-1108, PMID 24892638, PMC 5414803 (freier Volltext).

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[1] Atsukazu Kuwahara, Kyoko Matsuda, Yuko Kuwahara, Shinji Asano, Toshio Inui: Microbiota-gut-brain axis: enteroendocrine cells and the enteric nervous system form an interface between the microbiota and the central nervous system. In: Biomedical Research (Tokyo, Japan). Band 41, Nr. 5, 2020, ISSN 1880-313X, S. 199–216, doi:10.2220/biomedres.41.199, PMID 33071256.

[2] Elena Valassi, Massimo Scacchi, Francesco Cavagnini: Neuroendocrine control of food intake. In: Nutrition, metabolism, and cardiovascular diseases: NMCD. Band 18, Nr. 2, Februar 2008, ISSN 1590-3729, S. 158–168, doi:10.1016/j.numecd.2007.06.004, PMID 18061414.

[3] Alyce M. Martin, Emily W. Sun, Damien J. Keating: Mechanisms controlling hormone secretion in human gut and its relevance to metabolism. In: The Journal of Endocrinology. Band 244, Nr. 1, 29. November 2019, ISSN 1479-6805, S. R1–R15, doi:10.1530/JOE-19-0399, PMID 31751295, PMC 6892457 (freier Volltext).

[4] Atsukazu Kuwahara, Kyoko Matsuda, Yuko Kuwahara, Shinji Asano, Toshio Inui: Microbiota-gut-brain axis: enteroendocrine cells and the enteric nervous system form an interface between the microbiota and the central nervous system. In: Biomedical Research (Tokyo, Japan). Band 41, Nr. 5, 2020, ISSN 1880-313X, S. 199–216, doi:10.2220/biomedres.41.199, PMID 33071256.

[5] Gerard Clarke, Roman M. Stilling, Paul J. Kennedy, Catherine Stanton, John F. Cryan: Minireview: Gut microbiota: the neglected endocrine organ. In: Molecular Endocrinology (Baltimore, Md.). Band 28, Nr. 8, August 2014, ISSN 1944-9917, S. 1221–1238, doi:10.1210/me.2014-1108, PMID 24892638, PMC 5414803 (freier Volltext).