Marschalk reaction

The Marschalk reaction in chemistry is the sodium dithionite promoted reaction of a phenolic anthraquinone with an aldehyde to yield a substituted phenolic anthraquinone after the addition of acid.

The mechanism can be found in the book Named Reactions in Organic Chemistry,[1] and its more intuitive version is provided below:

One of the first applications of this reaction was reported in 1985.[2]

References

Mundy, Bradford P.; Ellerd, Michael G. & Favaloro, Frank G. Jr. (2005). Name Reactions and Reagents in Organic Synthesis. John Wiley & Sons. pp. 411–. ISBN 978-0-471-73986-9.
Krohn, Karsten; Miehe, Frank (1985). "Reaction of Anthrahydroquinones with α,β-Unsaturated Carbonyl Compounds". Liebigs Annalen der Chemie. 1985 (7): 1329. doi:10.1002/jlac.198519850704.

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[1] Mundy, Bradford P.; Ellerd, Michael G. & Favaloro, Frank G. Jr. (2005). Name Reactions and Reagents in Organic Synthesis. John Wiley & Sons. pp. 411–. ISBN 978-0-471-73986-9.

[2] Krohn, Karsten; Miehe, Frank (1985). "Reaction of Anthrahydroquinones with α,β-Unsaturated Carbonyl Compounds". Liebigs Annalen der Chemie. 1985 (7): 1329. doi:10.1002/jlac.198519850704.