Trifluoromethoxy group
The trifluoromethoxy group is the chemical group –O–CF
3. It can be seen as a methoxy group –O–CH
3 whose hydrogen atoms are replaced by fluorine atoms; or as a trifluoromethyl group attached to the rest of the molecule by a bridging oxygen atom; either leads to viable syntheses.[1] Compounds having this functional group are of some relevance as pharmaceuticals. One example is riluzole.
See also
References
- Synthetic Approaches to Trifluoromethoxy-Substituted Compounds A. Tlili, F. Toulgoat, T. Billard, Angew. Chem. Int. Ed. 2016, 55, 11726–11735; doi:10.1002/anie.201603697
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.